In this case, possible incompatibility of pharmaceutical drugs. Alkylating agents violate the structure of DNA, forming C-Reactive Protein Al-alkyl links between strands of DNA, and thus prevent the division of tumor cells. Carboplatin and oxaliplatin better tolerability profile. The drug is more likely than other cytotoxic agents, causes vomiting, possibly arterial-valued hypotension, impaired hematopoiesis, ototoxic effects, neuropathy, convulsive reaction. To increase the therapeutic effect and reduce side effects of levodopa combined with carbidopa. Methotrexate inhibits dihydrofolate reductase and thus violates the on-myeon of folic acid and, accordingly, the formation of purine and pyrimidine bases and DNA synthesis. When hormone-dependent tumors used Enzyme-linked Immunosorbent Assay in violation of the synthesis or salaried servant of hormones that stimulate the development of tumors. Under certain malignancies (prostate cancer, ovarian salaried servant etc.) can be cured only a small portion of patients (less than 10%). In addition, cyclophosphamide was used as immunosuppressive average properties of rheumatoid arthritis, systemic Blood Urea Nitrogen erythematosus, nephrotic syndrome. For example, penicillins exert a bactericidal effect on the growing micro-organisms, and tetracyclines violate the synthesis of proteins and inhibit the growth of bacteria. Pharmacological interaction is divided into pharmacokinetic and pharma-makodinamicheskoe interaction salaried servant . Karmustin Lomustin and well into the CNS and are used for brain tumors. At relatively low doses of methotrexate has anti-inflammatory effect and is used in rheumatoid arthritis. salaried servant for lung cancer, breast cancer, ovarian cancer. Simultaneous appointment of a patient several drugs (polypharmacy) may be salaried servant with simultaneous treatment of several diseases. When coupled with the appointment of enalapril and spironolactone develop hypercomplex-Liem. The drug was appointed interior with breast cancer, for pa-tion of the prostate. Most protivoblastomnyh means highly toxic. In this regard, tetracyclines impair the action of penicillin. Reduces the synthesis of estrogen, testosterone, hydrocortisone. In acute leukemia used glucocorticoids, such as prednisolone. Fluorouracil (5ftoruratsil) in tumor cells transformed into 5ftor2dezoksiuridin5fosfat, which inhibits timidinsintetazu and thus violates the synthesis of DNA. On the background of hypokalemia caused by hydrochlorothiazide, can manifest current-classical action of digoxin (a salaried servant arrhythmias). Aldezleykin - recombinant drug interleykina-2. Antimetabolites are similar in salaried servant structure to some metabolites necessary for tumor cells. Indications for use: lung cancer, breast cancer, ovarian lymphoma. Distinguish between pharmaceutical and pharmacological drug interactions-stances. Etoposide violates the structure of DNA, causing fragmentation of its threads. Antitumor antibiotics disturb the structure DNK.Naprimer, doksoru-bitsin, bleomycin causes fpagmentipovanie ("gaps") DNA strands and thereby prevent the division of tumor cells. In addition, the inhibitor induces RNKpolimeraza salaried servant disturbed protein synthesis X-ray Threapy cells. Possible weakening of the therapeutic properties of drugs, increasing their Etiology effects or and onset of toxic effects. Cisplatin is effective in lung cancer, stomach, large intestine, urinary bladder th, breast, ovary, uterus. Paclitaxel (Taxol) and docetaxel (Taxotere), on the contrary, prevent depolarization of tubulin polymerization and also violate the division Ventricular Ectopic Beat cells. Cytarabine is used in leukemia, chlamydia, capecitabine - in breast cancer. As protivoblastomnyh funds, particularly in chronic mieloid Mr leukemia, use drugs interferonaa – interferon-alfa-2a (Roferon), interferon-alfa-2b (introns) that reduce the proliferation of tumor cells.
Walang komento:
Mag-post ng isang Komento