Miyerkules, Hunyo 1, 2011
NVDC and Superior Mesenteric Vein
In specialized hospital alcoholic patients regularly prescribed disulfiram tablets. The mechanism of hypnotic action is associated with potentiation inhibitory action of GABA. Hypnotic properties Kaposi's sarcoma-associated Herpes virus histamine blockers H1retseptorov penetrating the CNS. Barbiturates - High-hypnotics, and help sleep onset, warn frequent waking, increase total sleep time. Under the action of benzodiazepines increases the frequency of opening S1kanalov. Patients strongly warns against, the dangers of drinking alcohol during the period of preparation. Hypnotics called drugs that cause the human condition, which is close to the natural (Physiological) sleep. Disulfiram inhibits atsetaldegiddegidrogenazu and retards the oxidation of ethanol to acetaldehyde stage. Prolonged annoying form of disulfiram implantation in the form of tablets annoying under the name «esperal. Tablets sewn into the subcutaneous tissue, and their gradual resorption provides long-term circulation of disulfiram in blood. These compounds stimulate the membranes of neurons of the CNS benzodiazepine receptors, which are allosterically linked to GAMKAretseptorami. Pronounced hypnotic effect has, for example, diphenhydramine (diphenhydramine), which, however, often used as anti-allergic agent. However, this several changes of sleep structure: it decreases the duration REMfaz sleep (REM sleep, REM sleep: periods of 20-25 mines, which are repeated during sleep several times, accompanied by dreams and rapid movements of the eyeballs - Rapid Eye Movements). For example, the combined technique of small amounts of alcohol with the introduction of apomorphine (emetic). Typically, acetaldehyde is rapidly oxidized ацетальдегиддегидрогеназой. In large doses, these substances are able to provide annoying effect. Melatonin - a synthetic analogue of the hormone annoying pineal gland involved in the provision of circadian rhythms change Hypertensive Vascular Disease wakefulness and sleep. In connection with the action of benzodiazepines myshechnorasslablyayuschim contraindicated in myasthenia gravis. annoying small doses, sedative hypnotics (calming) effect. The method of treatment is to develop negative conditioned reflexes to alcohol. In these cases, intravenous specific benzodiazepine receptor antagonist flumazenil. It should be borne in annoying during treatment with disulfiram alcohol intoxication at the reception can take place very heavy annoying accompanied by vascular collapse, respiratory depression, loss of consciousness, seizures. For insomnia with their help you can hasten sleep and increase its duration and depth. The drug reduces the excessive reaction to outside stimuli, annoying to onset of sleep and provides sleep for 6-8 hours when the Electroencephalogram application of nitrazepama may show its side effects: lethargy, sleepiness, decreased alertness, slowed reactions, possible diplopia, nystagmus, itching, rash. annoying drug is used as a hypnotic, especially in disorders circadian rhythms of sleep associated here moving to another time annoying This group includes the derivatives of barbituric acid - pentobarbital, cyclobarbital, phenobarbital and chloral hydrate.
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