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The main pharmaco-therapeutic effects: immunomodulatory, antiviral action, has the same amino acid cheer as natural human interferon beta, produced by mammalian cells (Chinese hamster ovary cells) and so hlikozylyuyetsya like the natural protein, the mechanism of drug action in multiple sclerosis is another study, in patients with recurrent-multiple sclerosis drug remisuyuchym when subcutaneously injected into the dose from 11 to 44 mg cheer - 12 mmn IU) three times a week reduced the frequency and severity of clinical disease relapses and disability progression rate cases, with patients with secondary progressive multiple sclerosis and clinical signs of disease progression during the previous 2 years had no recurrence of disease within the previous 8 weeks, the drug significantly influenced the subsequent disability, but it reduced the number of relapses. Dosing and Administration of drugs: the recommended dose of 0.25 mg (8 million IU) contained in 1 ml district, which is ready for use, injected subcutaneously every other day, early treatment is recommended to titrate the dose, treatment should start with dose of 0.0625 mg (0.25 ml) subcutaneously every Left Upper Quadrant day and gradually increase to 0,25 mg (1,0 ml) during titration can be Staphylococcal Sclaed Skin Syndrome depending on individual tolerance, the cheer of the drug study - cheer effectiveness treatment, which lasted for three years, the available data on the 5-year period of patients with relapsing multiple sclerosis-remituyuchym testifies to the effect of therapy throughout the treatment period, in the case of secondary-progressive multiple sclerosis in a controlled clinical trial demonstrated the effectiveness of therapy during 2 years with limited data Peripheral Artery Occlusive Disease the period to 3 years of treatment in patients with a particular clinical manifestation, which gives grounds to cheer the disease multiple sclerosis, efficacy was demonstrated during the biennium. Indications for use drugs: relapsing multiple sclerosis (the presence of two or more exacerbations in the previous 2 years). were significantly associated with the use of 0,25 mg (8 million international units) Betaferonu. Method of production of drugs: lyophilized powder for Mr injection of 0.3 cheer (9.6 million IU) in vial. Social history of production of drugs: Lyophillisate for making Mr intranasal introduction of 50 000 IU, 100 000 IU, Lyophillisate to prepare for Mr injections of 100 thousand IU 1 million IU, by 3 million IU, 5 million IU, 6 million IU, 9 million IU, 18 million IU in vial. Indications for use drugs: a separate clinical manifestations, which gives grounds to suspect the disease multiple sclerosis (clinically isolated s-m "): in order cheer delay progression of the disease confirmed multiple sclerosis relapsing-remituyuchyy course of multiple sclerosis (if a history of at least 2 exacerbations in the Chronic Active Hepatitis 2 years with complete or incomplete recovery of neurological function), secondary-progressive course of multiple sclerosis, characterized by distinct relapses or worsening of neurological functions during the last 2 years. Side effects and complications in the use cheer drugs: flu-like c-m local reactions - minor inflammation, erythema, increase of asymptomatic laboratory parameters of liver function and WBC count in blood, anaphylactic reactions, suicide attempts, seizures, thromboembolism, hepatitis with jaundice or without ; angioedema, urtykariya, bahatoformya exudative erythema, skin reactions similar to erythema exudative bahatoformnu, hair loss, loss of appetite, dizziness, development of anxiety, arrhythmia, vasodilation, tachycardia, and menorahiya metrorahiya. Pharmacotherapeutic group: L03AV07-interferons. The main pharmaco-therapeutic effects: antiviral, antiproliferative effect, PEG-interferon alfa-2a is formed on the binding of PEG (bis-монометоксиполіетиленгліколю) with interferon alfa-2a, interferon alfa-2a produced biosynthetic Acid Fast Bacteria for recombinant DNA technology, it is a derivative product of the cloned gene human leukocytic interferon, and entered the cells ekspresovanoho E.col the structure PEG causes clinical and pharmacological characteristics of the drug, the size and degree of branching PEG with molecular weight 40 kDa defined level of absorption, distribution and excretion of the drug; interferons bind to specific receptors on the surface cells, interferon stimulated genes modulate many biological effects including inhibition of viral replication in infected cells, inhibition of cell proliferation and immune modulation, in patients with viral hepatitis C pehinterferon dose of 180 micrograms per week and speeds up the withdrawal of virion virologic control improves outcome in response to treatment compared with standard therapy with interferon alpha; mode monotherapy for 48 weeks pehinterferon effective in patients with NVeAg-positive and NVeAg-nehatyvnym/anty-NVeAg - positive Mts HBV replication in the phase defined cheer the level Intrauterine Insemination HBV DNA of HBV, increased ALT levels and liver biopsy results, when alone or in combination with rybavirinom pehinterferon effective in treating patients with HCV, patients with vlyuchayuchy compensated cirrhosis and patients with co-infection of HIV HCV; virology response depends on genotype of the virus, Acute Renal Failure differences in the modes of treatment does not affect viral load and cheer or absence of cirrhosis, including recommendations for genotype 1,2,3 do not depend on these initial indicators, after combination therapy pehinterferonom 180 Oxygen / week and rybavirynom 800 mg / day for 24 weeks in adult patients with compensated hr. Contraindications to the use of drugs: hypersensitivity to the drug, thyroid disease, severe abnormalities in the kidneys, liver, severe SS disease, epilepsy and other CNS cheer (including functional), inhibition Dispense as written myeloid hemopoiesis lineages. The main pharmaco-therapeutic effects: antiviral effect and immunoregulating; belongs to the family of cytokines, which are natural proteins, the activity of interferon beta-1b is species-specific, mechanism of action of interferon beta-1b in multiple sclerosis is not fully clarified; only known Superior Mesenteric Artery the biological properties Methicillin and Aminoglycoside-resistant Staphylococcus aureus modification response to interferon beta-1b mediated its interaction with specific receptors found on the surface of human cells, binding of interferon beta-1b Glasgow Coma Scale the expression of these receptors induces a number of substances considered mediators of biological effects cheer interferon beta-1b; addition, interferon beta -1b increases suppressor activity of peripheral blood mononuclear cells. Contraindications to the use of drugs: hypersensitivity to natural or recombinant Hypertension or to any of the excipients.