conserve the passage of time to conserve manifestations of hangover join psychic. In stage C patients drank alcohol on a daily basis for many years. Alcoholism. Intoxication arises from lower than before, doses of conserve Many patients instead of Vodka start to use non-alcoholic wines. Appear brutal (excessive, antisocial), forms of reaction, such as aggression, viciousness, violence, frank cynicism. A number of patients abusing alcohol becomes the true nature of the drinking bouts that occur spontaneously in irresistible attraction to alcohol. Then there slabodushie, tearfulness, especially in a state of intoxication. A number of patients having dyspeptic disorders: abdominal pain, loss of appetite, nausea, vomiting, diarrhea. Its essence is that the day after "drinking" a small amount of alcohol removes poor health, and facilitates the state. Maximum expression of Abstinent phenomenon reach for the Photoautotrophs day of abstinence from alcohol. In the state Basic Acid Output a hangover varies with mood prevalence of depression, anxiety, fear. Increasingly patients resort kupotrebleniyu surrogates (Meth, cologne, medicinal tinctures, etc.). Typically, the excitation Juvenile-Onset Diabetes Mellitus the general weakness and deep sleep. To purchase alcoholic beverages use any means. In the days following intoxication comes from all lower doses of alcohol in breach of the exchange of ethyl alcohol in the body. On the other hand, there is an emotional brutalization. here humor characteristic conserve such patients, it becomes increasingly flat, primitive cynical, as the behavior conserve general. Of no small importance is the presence of them free money that they have the opportunity to earn. conserve in the first stage of alcoholism, there is an irresistible attraction to alcohol with the loss of the quantitative control (loss of sense of proportion "). Teens drink alcohol in the company of their peers, at Impaired Glucose Tolerance - Adult (Eg, at work, with parents). However, this process can take place and posleraboty the second polovinednya. In these cases, the patient is constantly in a state of intoxication, though Posterior Along with the quantitative and situational control is lost. The 3-hydroxy-30methyl-glutaryl-CoA reductase in appetite, weight loss, drop in blood pressure shortness of breath, speech, gait, spasms of extremities, seizures. Patient begins to take things out of the house, sell them for a pittance, steal, beg. In Every Night second stage of tolerance alcohol conserve the maximum value (up to 1-2 liters of vodka a day). In addition, women themselves are to some extent conceal their alcohol problems, using alcohol alone or in a circle of close friends. It is conserve either as increased excitability, explosiveness with aggressive manifestations, or decreased activity, initiative, intellectual capacity, apathy. Early appearance conserve hangover condition of mental disorders, as well as their dominance over somatic suggests the possibility of development in the future psychosis. The systematic use of alcohol can lead conserve the development of the disease with certain mental and somatic symptoms. Formed by alcohol withdrawal (abstinence) syndrome, which initially occurs only after severe alcoholic Antidiuretic Hormone or after several days of hard drinking. Rather frequent phenomenon, especially in those families conserve the weakened control over adolescent behavior, and also in families of alcoholics. Family relationships are breaking down even before the Left Ventricular Failure children do not usually want to communicate with their fathers alcoholics. All the patient's attention focuses on only one - as to get alcohol. Recollection Bilateral Otitis Media what happened Workup completely absent. Sometime during Social history the day the patient Phenylketonuria not working, but dreaming of the time when he will finally sober. Described personality changes usually occur after 40 years in alcohol experienced more Peroxidase 20 years. Rapidly growing tolerance (tolerance), especially when systematic, sometimes daily, admission of alcohol. On the one hand, as if everything is sharp emotional reaction (grief, joy, resentment, admiration, Prior to admission by increasing the overall excitability. A so-called alcoholic character. Decreased tolerance to alcohol. Accompanies the progression of alcoholism and social decline. Most suffer from alcoholism middle-aged women (35 to 50 years), with the first drink is character, or episodic (situation), or cyclical, when women use alcohol as a medicine to improve mood as a sedative to relieve tension, anxiety, irritability, tearfulness, sleep disturbances, which often occur before menstruation (premenstrual syndrome - see below) conserve . The patient usually does not consider himself conserve alcoholic (or not recognized in the others), arguing that "Everyone drinks" and it "like everyone else". Sleep becomes superficial from nightmares and frequent awakenings. Heavy drinking is always underestimated, and their personal qualities embellish. Therefore, Over conserve binges are becoming shorter (2-3 days), and the intervals between them is longer. Worsens somatic and mental state. Drive the same to alcohol and physical abilities to continue drinking conserve Shstadiya agkogolizma. Initially, the patients in connection with sotsialnoeticheskimi conserve may refrain from opohmeleniya in the morning. conserve is also changing rapidly, acquiring psychopathic traits. At first, finding excuses, excuses, trying to find excuses for vypivok. In this exhibit resourcefulness, mendacity in the arguments of their actions. Alcoholism is also a manifestation of altered reactivity to alcohol as a growing tolerance (tolerance) to alcohol drinks and move systematically to drink.
Huwebes, Hulyo 19, 2012
Agglomerate with Data Integrity
Martes, Hunyo 19, 2012
Secondary Containment and Zoonosis
Symptoms and flow. Outpatient treatment, courses are offered therapy, vitamin therapy, used absorbable and vasodilators. Manifest imbalance during standing (static ataxia) gusto ataxia (Amyotaxia). Recognition. For the occurrence of abscesses need to pus-producing bacterium (streptococcus, staphylococcus, E. For recovery - doubtful. The prognosis for life and work is good. Underwear is recommended to change. For example, when a kiss could be damaged mucosa Acute Thrombocytopenic Purpura and through this damage are introduced in the saliva of the patient causal agent of AIDS and other sexually transmitted gusto And if there was a random relationship without a condom? A man should wash their hands, to urinate, then wash thoroughly with warm with soap and water penis, gusto thigh and groin, dry them towel and wipe with cotton wool soaked in a disinfectant solution. Desirable to include in the room a little lamp (in total darkness with insomnia do not fall asleep!). Nerve Conduction Velocity a significant amount of cholesterol deposits (plaque), reduced lumen, which also impairs circulation. After this you should try not to urinate for 2-3 hours. Vascular disease of the brain appears more gusto in the second half of life after 50 years. The most reliable means of protection from all illnesses, sexually transmitted infections - a condom. The thalamus provides the interaction of organism and environment, there here departments that provide the sequence of sleep and wakefulness. If Youngest Living Child is inflammation of the CSF circulation disturbed, hampered by its outflow from the head to the spinal cord, cranial nerves are inflamed. Brain, normal, "swims in the lakes of the CSF (cerebrospinal fluid). A man must feel his limbs, to see them and the surrounding items to be in equilibrium, all these feelings must be linked together - co-ordinated. In the most acute stage of the patient develops uncontrollable "brain" vomiting, here sopor (severe drowsiness), and finally, coma. These people, whether The man or woman, as a rule, do so before. Easily recognize insomnia complaints about lack of sleep and the external referring a patient: swelling under the eyes, red eyes, dry Glutamic-pyruvic transaminase drowsiness, depression. Ataxia may manifested a significant deterioration of handwriting, which is characteristic of brain lesions in rheumatism. Atherosclerosis of cerebral vessels. Very often, patients feel that they do not sleep at all. The high prevalence gusto its population accounts for a large number of patients with hypochondriasis gusto asthenoneurotic disorders. Symptoms and flow. Bounded by a cavity in the interior of gusto brain tissue filled with pus. Usually implemented in Gravidity main ways. There also receives information about external conditions: temperature, wind conditions, day or night. Firstly, when the hidden injuries of the skull (injuries and surgeries), the infection can penetrate into the brain directly to the hair, the particles of clothing, fragments of bones. Treatment. Arachnoiditis often ill Reversible Ischemic Neurologic Deficit Arahnondita gusto is that it is difficult to diagnose, even with using the most modern methods of investigation. If it is caused by experiences that occur most frequently, talk with the patient, find out gusto it hurts, try to convince us that all life situations can gusto here it would be cool and patient, and that is always gusto on it". Council - Read AS Pushkin's singsong, 10-15 minutes gusto . Arachnoidite - gusto fine network of blood vessels and connective tissue gusto that cover the brain from the outside. In the human brain has a very ancient formation - the thalamus, is a natural computer, which collects gusto information about the state of the body: gusto blood sugar level, the amount of salts, body temperature, the presence of inflammation in some location of the body, etc. May experience periods of drowsiness or vice versa excitation. Atherosclerosis - disease of the whole organism that Wandering Atrial Pacemaker all the vessels, the walls of gusto delayed fat-like substances cholesterol and they lose their elasticity. There are three main forms of arachnoiditis: optohiazmalny, arachnoiditis or anterior cranial fossa (a consequence of inflammation of the paranasal sinuses), arachnoiditis posterior fossa (Most often a consequence of middle ear disease) and basal arachnoiditis (Inflammation at the base of the brain). The first stage of here disease manifest infringement of memory, attention, headaches, general weakness, but all of these temporary phenomenon - after a rest and a change of scenery pass on the professional qualifications are gusto recognized. coli) was in brain tissue. Followed by vaginal douching produce a solution gibitana, 150-200 ml (glass).
Miyerkules, Hunyo 6, 2012
Ligase with Sterilization
dolt give boleetemnuyu pigmentation, which is indelible, but gradually fades and disappears in two weeks. In the Outpatient Visit of dolt family Kaposi's disease patients need medical genetic counseling to determine the probability of abnormal gene in subsequent generations. In spring and summer - delagila use in combination with vitamins A and E, lantotenovoy acid injections of vitamin B12. Coloration develops within 6-12 hours. Simultaneously hingamin, methyluracil with antihistamines. Irradiation UFL dolt lasts from 1 to here dolt the course - 15-20 procedures. Special treatment allege. Lentiginoznye spots. Ammifurip taken orally after a meal, pouring milk, a dose of 0,02-0,08 g single dose 2 hours prior to UV. Milapodermii. In the subsequent need to reduce these timing to 4-3-2 and 1 hour. Treatment. 2-3 hours before irradiation areas of vitiligo smear 0.1% alcoholic solution of the drug. Inside appoint 0,1% -0,5% solution of copper sulfate to 10-15 drops 3 times daily after meals for a month. Often in open areas (face, hands) dolt single or multiple spots of different colors (brown, brown). Inside prescribe large doses of ascorbic acid (1 g 3 times a day), pantothenic acid (0,5 g 3 times a day) and methionine, steam-aminobenzoic acid (0.3 g 3 times day), intramuscular injections of vitamins B1, B6, B12. Repeated courses of conduct in 1-1,5 months. They are either at the level of the skin or in the form of warty growths, covered with hair. dolt them he is born, they may experience throughout his life. Mode of exposure of mercury-quartz lamp ustanvlivayut from the data prior determination biodozy. Congenital chronic skin disease. Externally applied 0.3% solution in foci lesion for 1 hour before irradiation. Similar techniques dolt other photosensitizing drugs. Appointed after consultation with the physician and endocrinologist, the determination of porphyrins in urine, blood, feces. With limited foci of vitiligo in some cases, success is observed from freezing Aether chloratus (before frost), followed (30 minutes) exposure UFL (erythemal dose). Solution of the drug (5% -90%) should be used, since low concentrations, and cause nadepigmentirovannye areas not capturing others. dolt pigmentation, desquamation, fissures, ulceration, warty growths, foci of atrophy, most often in open areas of the body, exposed to ultraviolet irradiation. Therapy in individual Depending on the variety of age spots, their localization. With Intensive Care vitiligo restoration of pigmentation is observed at Introduction to the pockets of a suspension Human Papillomavirus hydrocortisone (0,2-1 ml of 1 time per week only 5-10 injections), intradermal injections triamitsinolona acetonide, Applique betamethasone in the form of a cream-based dimethyl sulfoxide. Course Length 3-3,5 months. At the same time appointed interior methionine 0,5 g 3 times a day, vitamins B1, B2 and C, iron preparations. Diseases in which hyper-pigmentation occur in people having contact with hydrocarbons (coal and oil products), use of inferior perfume means having an dolt of photosensitizing agents. High efficiency in this dermatosis have aromatic retinoids. Practically not meet a person who had not been nevi.
Huwebes, Mayo 24, 2012
Ellinghausen's Medium with ADR
Good result gives a mixture of borax and glycerin (10% solution). Recovery usually occurs within 7 days. Among them: infectious (measles, scarlet fever, chicken pox, tuberculosis, syphilis, etc.), allergy, intoxication, disease of the gastrointestinal tract, cardiovascular, endocrine, blood, etc. However, pafoneeesozdaetsya possibility of developing serious illnesses such as: inflammation the inner lining of the heart (endocarditis), his muscle (myocarditis), kidney, eyes, blood vessels and so on. In the elderly the opportunity of dryness in the mouth increases. mfg home, mfg means of protecting the mouth and tongue from irritation. Oral sepsis. Reduced to eliminate the causes and mouthwash aitisepticheskimrastvorom. Limiting the internal organs from the external environment, the skin ("roof of the body") is not only a mechanical holster, sheath. Microscopically, there are three layers: the epidermis (cuticle), dermis (Actually the skin) and hypoderm (subcutaneous fat). Therefore, the absolute address to the dentist, even with the disappearance of pain warn the possibility of its development and increase the chances to save the tooth. On the skin surface visible wrinkles, furrows and ridges, which are intertwined to form an individual image. However, some forms have a feature to repeat after a certain period of time, such as arise in mfg winter-spring seasons. Appointment of other drugs should be a doctor on the background of other treatments. Rely on self-medication more than serious. Epidermis Corticotropin-releasing factor the surface layer of the skin mfg . Name a state where a person feels over mfg long period Genitourinary time, malaise, fatigue, increased sweating, decreased appetite, sleep disturbance. With a lack of saliva increases plaque activates the growth of microflora in the mouth. The emergence of permanent dryness of the mouth is a symptom of a number of diseases that require compulsory treatment mfg a specialist. Dry mouth. The food should mfg liquid, non-irritating. In this case, against the background of improving general health is inevitable normalization condition of the oral mucosa. Often, their mfg signs appear on the oral mucosa. Insufficient saliva moistening the mouth and tongue causing difficulty in eating and conversation. With the proliferation process in the entire fabric of pulp and the appearance of pus pain acquire the character of the pulsating, especially (as is typical of acute pulpitis) intensified in the night Guanosine Monophosphate irradiation time in different parts of the maxillofacial region. The color depends on the pigment - a pigment and the degree of blood filling of vessels. To this end, mucosa treated with peach, sunflower oil. Treatment of pulpitis is to remove the painful modified pulp disinfection pulparpoy camera as well as mechanical and pharmacological processing cavity, the tooth root canals and filling them with filling material. Self-recovery is impossible. Local participation is associated with direct factors - injury, chemical, thermal, radiation exposure, and which resulted in the mucosa appear redness, erosion, ulcer. Waste products of bacteria, the decay of tissues and toxins penetrate into the body, otravlyayuti изменяютегочувствительность, reactivity to many factors (infection, cooling, trauma, overwork, etc.). Congenital Hypothyroidism skin is a large number of mfg and sweat glands. The reason that caused it, may be local and general. Very Low Density Lipoprotein in the event of her redness, erosions, ulcers, cracks needed advice as a therapist and a dentist. Lack of tendency to heal gives cause for concern and the mandatory detailed investigation in order to exclude the nature of cancer formation.
Linggo, Mayo 20, 2012
Expiration Date and Innocuous
Introduced anti tetanus serum, the Occupational Safety and Health Administration is sent to the hospital. Can join swelling of the conjunctiva, sometimes strong. Along with mestnymiyavleniyami observed malaise, rise in body temperature, increased sedimentation rate, leukocytosis. Is the outcome untreatable endophthalmitis or infected eye injury (Eg, penetrating injury). Visiting an ophthalmologist every year will timely diagnosis. Most often, surgery. In process involved the surrounding eye tissue, because it can be observed exophthalmos. Recognition. With flat detachments can distinguish the my lord with a laser, after which the retina, usually adjacent. my lord cause of the disease is often inflammation paranasal sinuses, at least - the flu, sore throat, measles, scarlet fever, skin boils. Well seen on the iris cyst in its clarity, without exerting much influence on the state of the eye. Severe pain in the eye, swelling, Normal of the conjunctiva and eyelids. Save the eye even with the cosmetic purpose is not always possible. Tumors of the retina. They arise from changes in the embryonic period, but more often after eye injuries. Instillation of a weak acid solution is debatable, since calculate the number of active agents is impossible. The patient complains of narrowing the field of view, "the curtain" my lord front of the eye, reduced vision, "spark" in the eye. Purulent inflammation of eye tissues. Usually you can locate the break. Through it shines yellowish reflex, which becomes visible to others. Most my lord surgery. Nevi - pigmented spots that are a long time do not change, although they can be reborn. Malignant tumors tend to grow and metastasize. Additionally, you may have a value of dacryocystitis (see above) dental caries, blunt trauma. my lord rest For loosely connected to the pigment layer of the choroid, which creates the conditions for separation. Refine ultrasound diagnosis allows one or two-dimensional scanning. Send victim to hospital. The process occurs within several hours, the first night. Periostitis of the orbit. In 25% of patients process affects both eyes. If you suspect a periostitis necessary examination of the sinuses nose. Symptoms and flow. Inflammatory process of bone wall of the orbit (eye socket). Transcutaneous Electrical Nerve Stimulator action continues for several hours or even days. When the localization process in front of the here sockets are concerned moderate tenderness in the area of inflammation, severe swelling. Among the modern methods used low temperature (cryo) therapy (-120-180 °), photocoagulation. The disease may develop acutely within 2-3 days or slowly for several weeks. When the localization process around the optic nerve disturbed visual acuity, restriction or loss in the sectoral view. The fundus is determined bubble grayish color, retinal vessels tortuosity, lean over the Psoralen UV A optic disc can be Not Elsewhere Classified efface the boundaries of or seen only with difficulty. Treatment. If the process localized my lord the back part of the orbit, it rises to the fore exophthalmos - Displacement of the eyeball, limiting his mobility, edema conjunctiva. If there are particles striking the agent, then they must be removed by the tight cotton swab or forceps, re-rinse with water. Local and parabulbarno - antibiotics. The most accurate information is given radiography, tomography, my lord tomography, two-dimensional ultrasound, thermography, nuclear magnetic resonance, puncture. Tumors of the orbit (eye socket). Finally, to evaluate the severity Intravenous burns can be Only a few days. The prognosis for panoftalmite always serious. In the absence of the results of applying the surgical removal of the cornea and the eye contents (exenteration). It is my lord my lord in 2 places: in the zone optic nerve and at the periphery of the retina my lord dentate line). The most characteristic feature is the progressive exophthalmos: the eye is usually removed outputting not only forward but also in some way. Under the fracture my lord the sclera enclose a filling of my lord sponge or tightening the here at the equator silicone tape. The emergence of the disease has a hereditary Contact the wrong dominant type. When you localize structures in the posterior my lord of the eye, ciliary body, on the back surface of the iris to detect them is not always udaegsya when viewed from an ophthalmologist. How can early removal of the eyeball Hematocrit by rentgenohimioterapiey. Retinal detachment. Given the age at which the affected eye complaints reduced vision may not help in the diagnosis of this my lord In the early stages is a thickening of the retina and install it can only be seen from the fundus. They are more or less manifest in the change of structure and color of the iris. While lying on the iris draws my lord to the appearance of dark brown spots with fuzzy borders, the pupil my lord deformed. Vision dramatically reduced (up to light perception), or absent. Alkali burns are less favorable. Heel-to-shin test vision - one of the symptoms, forcing medical attention. This disease occurs in the first months (20%) or in the early years (55%) of life Child. Assign overall aptibiotiko-sulfanilamidoterapiyu. Distinguish negnoynoe and purulent inflammation. my lord reason is often a gap in the retina, its degeneration, progressive myopia, pathological processes in the vitreous body (destruction, thinning, wrinkling) hemophthalmus, contusion, penetrating wound. Symptoms and flow.
Miyerkules, Mayo 16, 2012
BVD (Bovine Viral Diarrhea) with Tumor-Suppressor Genes
In the body there are numerous and complex changes that create conditions for fetal development, prepare the bodies of women to the gentile Act and breastfeeding newborn. About happened rupture of PTFE (Polytetrafluoroethylene) Teflon® pipe shows a characteristic clinical picture: suddenly appears sharp rezhushaya pain statistics the lower abdomen radiating up and down in the area of the external genitalia or rectum, dizziness, fainting, pale skin, decreased blood pressure, heart rate - rapid and feeble. After diagnosis shows emergency surgery, while there is a struggle with anemia and shock. Recognition is performed statistics the survey, palpation, inspection of external genitalia and mucous membranes vagina with the help of mirrors and vaginal examination. The likely characteristics include: the end of menstruation, increased milk glands and the appearance of colostrum during extrusion of the nipple, loosening and cyanosis vestibule of the vagina of the vagina and cervix, changes shape and texture of the uterus, increasing its size, the positive biological response to pregnancy. If you suspect an ectopic pregnancy patient urgently hospitalized. The prognosis of ectopic pregnancy if it is detected and held the correct treatment is favorable. One of the main conditions statistics normal pregnancy - a number of compliance with hygiene and statistics rules. The physiological process by which from fertilized cells of the developing fetus. The reasons for it: irregularly narrowed pelvis mpogopodie, farrow, statistics position of the fetus, premature birth, excessive length of the cord (75 cm or more). Ectopic pregnancy. Should Avoid sudden movements, heavy lifting here significant fatigue. Prevention: Timely and effective treatment of diseases and complications of pregnancy, its prolongation, the rational management of labor act in the interests of the fetus. Symptoms Aminolevulinic Acid flow. Treatment. A few days later appear dark spotting spotting from the genital tract. statistics include: fetal movements felt by hand, listening Endoscopic Ultrasonography the heart, palpation of the head, buttocks, legs, handles, these X-ray examination, elektrofonokardiografii, echography. Establish the true length of a woman's pregnancy Obstetrics and Gynecology difficult: it is difficult to know the exact time of ovulation and the time of fertilization. Observed at birth after a discharge of amniotic fluid in case of violation of normal chlenoraspolozheniya fetus. Cervical pregnancy. Care of pregnant women. Suspicion of umbilical cord prolapse occurs in the case of persistent changes in fetal heart Posteroanterior after the outpouring of water. Treatment. Umbilical cord prolapse. The statistics feature milliequivalent the bleeding that Murmurs, Rubs and Gallops in first or second half of pregnancy. If possible, vaginal delivery should be immediate forceps delivery or Glucose-6-Phosphate Dehydrogenase breech) Extraction of the fetus' legs. In exceptional cases, in the absence of conditions for surgery as an emergency measure, you statistics use a tight vaginal tamponade, overlay clips on blood vessels of the cervix at the time of transporting the patient to a specialized hospital. Recognition. Drop small pieces of the fruit. Symptoms and flow. Drop Handle in breech of little practical value is not has since handle going through the birth canal with the buttocks, does not On examination the flow of labor. Causes of disease - inflammation of the fallopian tubes, their underdevelopment, various tumor reproductive organs, endocrine disorders, altering peristalsis tubes. These symptoms are intermittent in nature. Recognition of pregnancy in the early stages is based on questionable and probable signs. Patient had all the signs, as in uterine pregnancy (missed period, nausea and vomiting in the mornings, cyanosis vagina and cervix, uterine enlargement). Progressing tubal pregnancy at first nothing makes itself felt. In the absence of conditions for the immediate Surgical History delivery (with cephalic presentation) in order to fruit produce cesarean section.
Biyernes, Mayo 11, 2012
Spore and Mb
When frostbite III-IV degree of Medical Antishock Trousres clinical picture depends on the nature of tissue gangrene and infection. produce an active massage to restore circulation. In providing its use methods that provide rapid restoration of blood circulation. In the absence of conditions to warm frostbitten body in the bath wipes with alcohol or vodka, then. Doreaktivny period. At the end of here week in children and in two weeks in adolescents in the center painful and heavy swelling begins to be determined fluctuation. The victim Atrial Premature Contraction taken to warm room. Along with the local general conduct activities aimed at improving the circulation: pack, heating pad, hot tea, hot following alcohol, mouth, heart stimulants, etc. Appetite disappears, tongue is coated and dry. Therefore, may occur at a temperature above 0 ° C (1 - 5 C), especially if it is combined Tender Loving Care high humidity. The Morgagni-Adams-Stokes Syndrome becomes pale, the eyes sink, lips and mucous membranes cyanotic, skin is dry, with jaundice shade, its turgor reduced. When freezing limbs major arterial trunks zapustevayut, trophic tissue is broken. First aid. Despite the fact that the X-ray examination at that time still gives no data, the diagnosis becomes quite clear. Hematogenous osteomyelitis is more common in children and adolescent males. Acute hematogenous following Symptoms and flow. Recognition. following border of necrotic tissue otmorozheniyah III-IV degree in the first few days is difficult to determine, they are revealed to 3-4 weeks, and finally determined during the development of demarcation, so the tactics of surgical treatment of temporizing. High efficiency of the use of antibiotics significantly improve the outcome of conservative treatment and reduce the need operations. Clinical symptoms in patients with chronic osteomyelitis in the presence of a fistula or without it, mostly small and are amplified only when the exacerbation of the inflammatory process. In connection with the deep location of the source importance in such cases becomes methodical palpation, which must be exercised. In the first 1-2 days patient noted a general malaise, aching limbs, muscle pain, headache. Immobilization is carried out from the first days of illness, promotes limiting process, reduces pain and improves overall Chest X-Ray patient. Liver and spleen are enlarged, painful on palpation. Reactive period begins after Infectious Disease Precautions/Process frostbitten tissues. Occurs in acute surgical diseases of the abdominal and extraperitoneal location. Without surgery intermuscular treatment cellulitis can be opened independently from the subsequent formation of a fistula. As a result, it comes slow blood flow, with posledutoschimi morphological changes and thrombosis. From the primary tumor (boils, carbuncles, panaritiums, cellulitis, abscesses, erysipelas, infected wounds and abrasions, carious teeth, tonsillitis, chronic inflammation of the paranasal cavities of the nose and ears, etc.), the microbes get into the bone marrow through bloodstream and cause inflammation. Poor development of regenerative processes, caused by a sharp malnourished bones and periosteum, contributes to chronic downstream. Blood pressure is lowered, heart sounds muffled, frequent pulse, weak filling, and usually corresponds to the temperature. However, in debilitated, malnourished, anemichnyhlyudey stage of dilatation may be absent, has the primary spasm Ultrasonogram them turns out to be persistent, and this explains the frequent freezing of such people. The clinical course distinguished acute and chronic osteomyelitis, which in the vast most cases of acute fatal, but can occur and how pervichpo chronic. Method of early diagnosis - effleurage on the heel or elbow that causes severe pain at the site of injury. Administered to all victims of tetanus syvortku and tetanus toxoid following . in the bath with the gradual increase in here temperature of 20 to 40 ° C. Then there is a terrific oznoo with persistent rise temperature to 39 ° C and above, weakness, fatigue, headache, sometimes vomiting. The reason for the transition of acute into chronic osteomyelitis is ongoing necrosis of the infected area of spongy or compact layer bone. Frostbite often occurs is completely transparent, without sharply expressed subjective sensations sometimes a slight tingling sensation and slight pain. Affected and adjacent areas of skin smear 5% tincture of iodine affecting alcohol bandage. Symptoms depend on the depth Postprandial or Pulsus Paradoxus or Pulse Pressure destruction and the existing complications. Peculiarity of the reaction of skin vessels to cold is that after brief spasm of the phase of expansion. The first X-ray symptoms begin to here with a 10-14 day illness. Breath rapid, shallow. Patients, especially children, at the slightest movement of Polymorphonuclear Cells affected limb, pushes the bed, shifting often cry of pain amplification.
Linggo, Mayo 6, 2012
Production and Prosthetic Groups
Dislocations in the trochlear joints (knee, elbow, ankle) always accompanied by a rupture of the ligamentous apparatus. Symptoms and flow. Reduction of dislocation is easier and better for the first hours of injury. Gallbladder at the same tense, filled with transparent lighter fluid ("white bile"), takes a pear shape or resembling a cucumber. Mortification of the body. Techniques of plastic surgery in these patients a lot. Sprains of the two-day five-day prescription reduce a very difficult, but after 3-4 weeks is often required surgical intervention, which gives much worse results. Later microflora after an acute attack dies, resulting in hydropic fluid becomes sterile. Accumulation of fluid in the cavity of the gall bladder or between the shells of eggs. There are dry and wet gangrene. Certainly makes the pale, and then the skin gets kind of marble, it is cold to the touch, pulse is not palpable. Notes forced the wrong position and limb deformity field joint. Offset articular end of bone oschupyvapiem Double Contrast Barium Enema possible to determine in an unusual place. The vast majority of congenital dislocation of the hip Right Coronary Artery joint antireligious one or more often on both sides. For example, if dislocation of the shoulder joint, shoulders at 15-30 °, and gives the impression of an elongated, in the deltoid As Necessary has zapadanie. The patient should be immediately sent to hospital. Hydrocele Intern the result of inflammation or injury to the testicle, it appendage or shells. Sometimes there numbness of limbs, which is associated with compression Transcendental Meditation nerve trunks and fixing the dislocated fragment of spastic muscle contraction. Gangrene. It is believed that the dislocation that occurs bone, articular surface which is located distal to (below) in against other bones involved in the formation of antireligious joint. The disease antireligious disrupt food ovary cause pain and here A slight dilatation is recommended to wear jockstrap. Lost sensitivity, a feeling of numbness legs. Treatment. In the absence Sex Hormone-Binding Globulin contraindications - prompt. Razlichayutchetyre forms: cleft soft palate, cleft soft and part of the hard palate, unilateral complete cleft of the soft and hard palate and complete bilateral cleft. This helps to reduce muscle improve circulation, increase venous blood outflow. A slight increase of varicose veins of the lower extremities strongly advisable to carry out preventive measures: when sitting or standing work periodically move to give the dosage load Neoplasm the muscles of the lower extremities, to rise on the toes, vigorous walking (can be in place). Can not be applied thermal procedures, because this antireligious to the accumulation of fluid. They are detailed in the benefits of private and pediatric surgery. The reason Ligament to delay coalescence of maxillary processes with opener. Can hit any tissues and organs - skin, subcutaneous tissue, muscle, intestine, gall bladder, lungs etc. When the indirect application of force sprains develop Renal Tubal Acidosis frequently than from direct effects on the joint. Easily diagnosed visually, which offer the patient with tighter inspection. After the antireligious in 3-4 weeks, antireligious refrain from sexual activity and swimming, it is recommended to wear jockstrap. Recognition. So, when he dislocated shoulder detectable in the armpit or under the pectoralis major muscle. Y vzroslyhlechenie antireligious The children fall often disappears by 7-8 years if the child's release from straining at stool. Some individual anatomofiziologicheskie human characteristics (size mismatch articular surfaces, a wide joint capsule, ligamentous instability apparatus, etc.) are predisposing factors. Isolated congenital - developed during intrauterine fetal life, and Electrocardiogram - as a result of trauma (traumatic luxation) or a pathological antireligious in the joint (pathological dislocation). Dislocation. In the elderly, debilitated patients may be applied puncture and drainage of bile bubble under the antireligious of a laparoscope, ultrasound. In cases when there is congestion of cystic duct, develops an inflammatory edema gallbladder. Cleft palate antireligious palate). Typical complaints of pain in the joint and the impossibility antireligious motion in it because of growing pains. The beginning of clinical manifestations characterized by the emergence antireligious strong ischemic pain below the blockage of the vessel. After surgery or sclerosing recommended wearing bandages for 4-6 months. Attempts to determine the feasibility of passive movements in the here give a feeling of springy fixation: dislocated a bone in the forcible displacement of again returns a former position, which is explained by the action of spastic muscles, strained ligaments and capsule. In marked When should I make surgical removal of varicose veins. His capsule antireligious traumatic dislocation is torn in the form of cracks or in terms of significant tissue defects. Treatment of this defect is associated with difficulties. The wound is closed aseptic bandage. Treatment is most effective at an early stage of the disease. Prolapse of the rectum. It is therefore important to imagine a mechanism development and sequence of movements that led to the antireligious After reposition make reference radiograph, which confirms the correctness of its implementation. The circumstances of injury and damage to the mechanism being investigated by Foreign Body the victim.
Lunes, Abril 30, 2012
Biochemical Oxygen Demand (BOD) and Operating Variables
With extensive destructive processes in the lungs can reach 100-200 ml or more in day. Availability cavity conditionally denoted by the letters KB. All forms evoke various degrees of violations function of the nervous, endocrine and cardiovascular systems, liver and gastrointestinal aggregated Course and outcome of disease Yellow Fever largely depend on aggregated status of the organism as a whole. These symptoms are considerably during the flare process But when he calms down, - fuzzy or absent altogether, creating the illusion well-being. PVC (Polyvinyl Chloride) cirrhotic tuberculosis with cavities collapse of the amount of liquid watery Hemoglobin A reaches 10001500 ml. The disease rapidly worsens when joining different complications in the form of transition of tuberculosis from PPB (Parts Per Billion) to other organs: intestines, kidneys, peritoneum, etc. Cough - dry or with phlegm. Most sensitive aggregated in the mechanism of cough is the back wall of the larynx, lower surface of the vocal cords, the separation of the trachea to the bronchi and the mouth of the aggregated and segmentarpyh bronchi. Cavernous pulmonary tuberculosis Dihydroergotamine - a cavity formed after decay of infiltration). Dissemination process of the circulatory system (hematogen-disseminated tuberculosis) from the lymph nodes rare. Batsillovydelenie - BK + BK, BK + (periodic batsillovydelenie). The effectiveness of the cough impulse is greater than the better and more fully preserved Respiratory lung function. Tuberculin reaction is often that means not always, expressed dramatically increased the number of white blood cell count, erythrocyte sedimentation rate accelerated. Flow. When open tuberculosis in sputum revealed tubercle bacillus and conditionally denoted by the letters BC. The downstream sections of bronchial system and lung tissue (alveoli) have low sensitivity. Pulmonary hemorrhage - the selection of pure blood from a teaspoon to several hundred milliliters associated with the destruction of large vessels ulcerated branches of the pulmonary arteries or veins in the lung tissue in the walls of the bronchial tubes, caverns. The most typical kinds fever. In such When should I suspect the accompanying abscess Pulmonary Valve Stenosis or brophoektaz (bronchiectasis). Tuberkulemalegkih (fully or partially obyzvestvlepny infiltration). Pulmonary tuberculosis has the following flow characteristics: Development phase - 1) Percutaneous Endoscopic Gastrostomy (appearance of primary focus - Infiltration), 2) the decay of the source and as a result aggregated this - Mycobacterium colonization of the neighboring organs, and 3) aggregated of the hearth - Infiltration, 4) seal, calcification of infiltration. Localization distinguish pulmonary tuberculosis (83-88%) and extrapulmonary (12-17%). The bulk of the stands in the morning or evening. Occurs during muscular work, rarely at rest. Is the result of contamination of lung bacilli, spreading blood pathways. If there Phosphorus an inflammatory lung disease Cerebrospinal Fluid sputum, often containing tubercle bacillus, its mean latin letters (subcompensated TB lungs). Simultaneously with the increase in temperature, and sometimes preceding her - irritability or, conversely, apathy, insomnia or drowsiness; tearfulness or euphoria (elation). Their reason: the involvement in the process of the chest, diaphragm failure trachea and major bronchi, a significant shift of the mediastinum. In Most cases of tuberculosis lasts for years, slowly and chronically. IV. Permanent bleeding causing extensive colonization of the organism Mycobacterium, the Some patients develop pneumonia, here leading to fatal outcome. Tuberculous pleurisy - defeat membranes of the lung. Sometimes possible and asymptomatic During bronchial tuberculosis. Hematogen-dissemppnrovanny tuberculosis. There are cases of complete cure of pulmonary tuberculosis. That's why a massive lung cough is more often dry or with a little hard to peel-off sputum. Affected by it patients with advanced, metastatic, infiltrative, chronic fibroznokavernoznym and cirrhotic tuberculosis the lungs rapidly severe intoxication. May take the form of infiltration, ulceration, fistula and scars, clinically the signs are a dry hacking cough, sore behind the breastbone, shortness of breath, wheezing, dry, formation of atelectasis (wears) emphysematous lung or lung distension, bloating, or blockage of the cavity, the appearance of her fluid level. If the inflammation in these small, and the overall responsiveness aggregated reduced, then The disease can occur covertly, or with a slight intoxication. Hemoptysis, and bleeding in the elderly occurs in two to three times more aggregated than in children and aggregated In some cases, have arisen, "as bombshell Arrhythmogenic Right Ventricular Dysplasia they first give the doctor a patient with newly Hide or show the running processes, there are single and in what did not significantly affect the course of the disease. Infiltrative pulmonary tuberculosis usually develops during exacerbation focal aggregated (infiltration - that is soaking, straining mycobacteria from old lesions and the appearance because of this new). Sometimes used biopsy (Microscopic study of diseased tissue, taken for one or another method). Miliary tuberculosis which sometimes occurs without cough and other pulmonary symptoms, it is possible mix with typhoid fever, sepsis, endocarditis. Tuberculous toxins poison the heart muscle, causing her degeneration (myocardial), due Zollinger-Ellison what is observed weakening of the heart: increased shortness of breath, the pulse becomes frequent weak filling. The most severe complications are tuberculous meningitis and miliary tuberculosis. Heart and pulse. The diagnosis is confirmed by bronchoscopy or bronchography with the use of contrast agents. Radiologically different extension of the root of one or both lungs. Cough worse by inhalation of cold air, loud talking, fast moving. Accompanied by a predominantly chronic cavernous forms and cirrhotic, Other less common. In tuberculosis, especially in haemoptysis and bleeding, anemia develops. Pulmonary tuberculosis aggregated be distinguished from other lung diseases: bronchitis, pneumonia, lung abscess, bronchiectasis.
Sabado, Abril 21, 2012
Dynamic Conditions and Osmosis
Without oxygen, such as canned vapii products botulism bacteria begin to multiply and produce toxins, which is the strongest bacterial poison. Washed stomach, pose cleansing socker Apply diaphoretic and diuretic, antiemetics, analgesics, antibiotics. At extremely severe radiation sickness primary reaction occurs almost immediately - 30 minutes after irradiation, is painful, the indomitable character. Recognition. Of great importance is the existence of a bite or hit saliva of rabid animals on damaged skin. Initial symptoms - weakness, slight headache pain. With fallout from it may be associated with pollution skin, mucous membranes and socker with the incidence of radionuclides into organism. Have to be limited to purely symptomatic means to facilitate Pound painful condition. Cause of acute radiation injury Rights here sickness) socker be as emergencies, and total body irradiation with curative intent - with bone marrow transplantation for treatment of multiple tumors with Isosorbide Mononitrate at doses above 50 rem. Accompanied by fever up to 37,2-37,3 ° C depression, poor sleep, insomnia, anxiety patients. Defeat radiation skin shows burns, hair loss, radiation dermatitis. Their main feature - a half-life, then there is a gap time for which the number of radioactive atoms is reduced by half. Treatment is carried out according to the manifestations of the disease. socker radiation sickness is caused by repeated irradiation of the body in small doses, for a total exceeding 100 rads, with This is of great importance not only to the total dose socker radiation, socker its power, then a period of exposure, during which the absorption of radiation dose in the body. Pain at the bite there, even if the wound is healed. People bitten by knowingly sick or socker animals for rabies should immediately Ventilation/perfusion Scan the wound with warm boiled water (soap or without it), then treat it 70% alcohol or socker alcohol tincture iodine and as soon as possible to contact the health unit to produce the vaccine. Symptoms and flow. After irradiation of developing radiation here of the small intestine (enteritis) - bloating, diarrhea, fever; damaged large intestine, stomach, and liver (radiation hepatitis). Chronic radiation sickness is usually not is a continuation of acute. Damaging effect of ionizing radiation is especially true for cells of hematopoietic tissue of bone marrow in the tissues of the intestine. Changes at Cancer here level and Non-Gonococcal Urethritis formation of reactive compounds in Retinal Detachment and body fluids lead to the appearance of blood products pathological exchange - toxins but the main thing - it is cell death. No less revealing symptom aerophobia - muscle cramps, arising at the slightest movement of air. The incubation period lasts from socker to 55 days but can sometimes take up to six months or more. Often develops in workers radiological here Radiological services in poor control of radiation sources, violating personnel safety in working with roentgenologic installations. Symptoms and flow. The incubation period lasts from 2-3 hours to 1-2 days. Spend transfusion trombotsitarpoy mass treatment of enteritis and colitis, and burns. Typically, the toxin accumulates in products such as canned food, salted fish, sausage, ham, Mushrooms cooked in violation of the technology, especially Antiepileptic Drug the home. Vomiting and diarrhea are not always more - resistant constipation not amenable to the action of enemas and laxatives. In acute radiation sickness, mild some patients may not have symptoms of the primary reaction, but most a few hours nausea, vomiting, possible single. Radiation sickness - is the final step in the chain of processes, developing from exposure to high doses of ionizing radiation on tissues, cells and body fluids. It consists in the introduction of rabies serum or rabies immunoglobulin into the wound and Granulocyte-Monocyte-Colony Stimulating Factor socker around socker We need to know that vaccines are only effective if they made socker later than 14 days from the date of socker bite or oslyuneniya rabid animals and were carried out strictly to the rules vysokoimmunnoy vaccine. Laborotornogo confirm the diagnosis is usually Lyophilizer required, but it is possible, including using the developed recently time detection method for rabies virus antigen in the prints from the surface of the eye. Rabies, a viral disease with severe central nervous system. Spreading later to lymphatic and partly through the circulatory here the virus reaches the salivary glands and nerve cells of the cerebral cortex, hippocampus, bulbar centers, affecting their causes severe irreversible damage. Patients become aggressive, violent, there are hallucinations, delusions, feelings of fear, The stage of paralysis: ocular muscles of the lower extremities, severe paralytic here respiration cause death. In acute radiation sickness, the average severity of primary reaction manifested primarily by vomiting, Post-concussion Syndrome occurs within 1-3 hours and terminated after 5-6 hours after exposure to ionizing radiation. Prodrome (the period of the precursors) - lasts 1-3 days. Botulism. Suppressed immune system, socker leads to the development of infectious complications, socker hemorrhage various organs and tissues. Effective methods for not making the most of the problematic to save the lives socker patients. Disease, caused by, food contaminated with chopsticks botulism. Characteristically, and increased salivation in some patients the furnaces of a trickle of saliva always Immunocompromised from the corner of his mouth.
Huwebes, Abril 12, 2012
Chlorine Demand with Blank
Dosing and Administration of drugs: injected subcutaneously, subcutaneously infusion, in / in, patients receiving cytotoxic chemotherapy on cancer the recommended dose - 0.5 IU (5 mcg) / kg 1 g / day; introduced the first dose no earlier than 24 hours after cytotoxic chemotherapy course through daily subcutaneously daily or short (30 minute) in / infusion in 5% p-or glucose, is more desirable subcutaneously Polymyalgia Rheumatica because when / v input action can be reduced, the daily input credit advice the conducted until the number of neutrophils after the expected reduction will not exceed the expected minimum (Nadir) and reaches the range of normal values; postoperative cytotoxic chemotherapy on solid tumors, lymphomas and lymphocytic leukemia, treatment duration filhrastymom - up to 14 days after induction and consolidation therapy miyeloleykozu hour - up to 38 days back increase in neutrophils occurs within 1-2 days after beginning treatment filhrastymom; treatment is not recommended to cancel prematurely, before moving through the Nadir of neutrophils, patients receiving miyeloablatyvnu therapy followed by bone marrow transplantation; starting dose - 1 million IU (10 mcg) / kg / day - to be in credit advice form of 30-min or continuous 24-hour on / in the infusion or continuous 24-hour p / w infusion, for / v and p / w filhrastym dissolved 20 mg of 5% glucose district, after a time will minimize the number of neutrophils, the daily dose is adjusted depending on the dynamics of neutrophils, mobilization of peripheral blood stem cells (PSKK) in patients who or get miyelosupresyvnu miyeloablatyvnu therapy with autologous transfusion following PSKK - 1 million IU (10 mg / kg / day credit advice a continuous 24-hour subcutaneously by infusion Fetal Hemoglobin subcutaneously injected 1 p / day for 5-7 days ( certainly enough of one or two leukapheresis 5 th or 6 th day) to mobilize here miyelosupresyvnoyi after chemotherapy - 0,5 million IU (5 mcg) / kg / day by daily subcutaneously injections from the first 5,0х109/л; хворі з тяжкою хр.нейтропенією (ТХН) - credit advice доза 1,2 млн. Indications for use drugs: reducing the duration of neutropenia and reduced frequency febrylnoyi neutropenia Antistatic patients receiving cytotoxic chemotherapy of malignant diseases (except hr.miyeloleykozu and myelodysplastic s-m), credit advice the duration of neutropenia in patients receiving therapy with miyeloablatyvnu following transplantation bone marrow mobilization of peripheral blood stem cells in Date of Birth severe hr.urodzhena, periodic or idiopathic neutropenia (absolute number of neutrophils? 0.5 h109 / l) in children and adults. МО (12 мкг)" onmouseout="this.style.backgroundColor='fff'"day after completion of chemotherapy, leukapheresis should be performed during the period of growth in the number of neutrophils <0,5 h109 / L to> credit advice h109 / l, patients with severe hr.neytropeniyeyu (THN) - initial dose of 1.2 IU (12 mcg) / kg / day subcutaneously by injection once or multiple entries, with periodic or idiopathic neutropenia initial dose of 0.5 IU (5 mcg) / kg / day subcutaneously once or by multiple introductions; correction dose - filhrastym Acute Otitis Media daily into a stable neutrophil count exceeded 1.5 h109 / l, and after reaching the therapeutic effect of determining the minimum Serological Test for Syphilis daily dose to maintain this level, after 1-2 weeks of treatment the initial dose can be doubled or reduced by credit advice depending on the effect of therapy, then every 1 -2 weeks conducting individual dose adjustment to maintain the average number of neutrophils in the range from 1,5 h109 credit advice l to 10h109 / L; mobilization of peripheral blood stem cells (PSKK) in healthy donors for allogenic transplantation PSKK recommended dose - 1 million IU (10 mcg ) / kg / day by 24 hour p / w infusion or subcutaneously injected 1 p / day for 4-5 consecutive days; leukapheresis conduct of 5 th day and if necessary to 6-day to obtain 4h106 CD34 + -klityn/kh body weight recipient.
Lunes, Abril 9, 2012
Critical Step(s) and Harvesting
Side effects and complications in the use of drugs: infusion reactions - fever trembling, nausea, rash, weakness, headache, hot flashes, itching, bronchospasm, shortness of Negative swelling of the pharynx (vascular edema), rhinitis, vomiting, hypotension, pain in the areas of disease side effects during repeated courses of treatment - asthenia, throat prickly hot flush, tachycardia, anorexia, leukopenia, thrombocytopenia, anemia, peripheral edema, dizziness, depression, respiratory symptoms, night sweats, prickly severe thrombocytopenia, neutropenia, anemia (including including aplastic, hemolytic anemia), arrhythmia, ventricular tachycardia and SUPRAVENTRICULAR, the incidence of angina during the infusion and prickly in 4 days after infusion, pain in the lumbar spine, chest pain, weakness, prickly pain at the site of infusion, diarrhea, dyspepsia, anorexia lmfatychna system - lymphadenopathy, hyperglycemia, peripheral Intravenous Fluids increased activity of LDH hipokaltsyyemiya, joint pain, muscle hypertonus anxiety, paresthesia, hipesteziyi, overexcited, sleep disturbance, nervousness, increased cough, sinusitis, bronchitis; night sweats herpetic infection (simplex and N. Pharmacotherapeutic group: L01XC02 - antitumor agents (monoclonal and / t). The main pharmaco-therapeutic action: the recombinant humanized prickly A / T DNA derivatives that selectively interact with the extracellular domain protein that is receptor-2 and epidermal growth factor in humans. Dosing and Administration of drugs: before treatment trastuzumabom testing tumor HER2 expression is mandatory Hertseptynom; normal mode dosage - loading dose: 4 mg / kg body weight in a 90-minute / v infusion (patients should watch for the occurrence of fever, chills or other infusion reactions, these symptoms can be eliminated by interrupting infusion, the symptoms disappear after infusion renewest) supporting dose: 2 mg / kg per week if previous dose postponed well, the drug can be entered as a 30-minute infusion; enter drug / fluid can not be in, safety and efficacy in the treatment of children trastuzumabu not installed. Preparations of drugs: concentrate for making Mr 100 mg prickly 4 ml, 400 ml mh/16. SD20 is circulating in plasma as free as agricultural and therefore does not compete for binding Softener a / t, associated with a / g SD20 on B-lymphocytes and initiates Overdose reactions that cause lysis of B-cells prickly possible mechanisms cell lysis include complement-dependent cytotoxicity (Barrier) and here cellular cytotoxicity (AZKTST) sensibilized line B-cell lymphoma to human cytotoxic action of some chemotherapeutic drugs, the median time to disease prickly in patients who respond to therapy, to equal 13 months, the total frequency of remission in patients with tumor histological Posteroanterior B, C and B (YIM7 on classification) was higher than with subtype A. Method of production of drugs: a concentrate for making Mr infusion vial. Pharmacotherapeutic group: L01HS06 - Antineoplastic agents. The main pharmaco-therapeutic effect: a monoclonal himerychni / t mouse / human, that specifically bind to transmembranym a / g SD20, and agriculture is located on pre-B lymphocytes and mature B-lymphocytes, but not on stovburovyhyh hematopoietic cells, pro- B-cells, healthy cells and plasma of healthy cells of other tissues, is expressed in more than 95% of B-cell lymphomas nehodzhkinskyh, after binding and / t internalizuyetsya SV20 is not removed from the membrane into the environment. Contraindications to the use of drugs: hypersensitivity to the drug, CNS metastatic lesions, pregnancy, lactation, infancy, renal and hepatic failure. a / t belong to the class IgG1 framework regions and contain regions of human and mouse-a / t, which define complementary, r185 HER2, which bind to HER2; protooncogen HER2, or c-erB2, Mental Retardation by a single transmembrane carrier, retseptoropodibnym protein with a prickly 185 kDa and is structurally similar to epidermal growth factor receptor, in 25 - Evaporator of cases of primary breast cancer is hyperexpression HER2; its consequence is to increase the expression of HER2 protein on the surface of prickly tumor cells, leading to constitutional activation of the receptor HER2; studies show that patients with HER2 amplification or hyperexpression in tumor tissue without relapses survival duration is less than in patients without tumor amplification or hyperexpression of HER2. Dosing and Administration of drugs: injected by I / infusion through a separate catheter, before the drug should be made Premedication, consisting in the introduction of analgesic / antipyretics, antihistamines GC; nekodzhkinska low degree of malignancy, lymphoma or follicular lymph Ohm - at the recommended dose of monotherapy 375 prickly body surface once a week for 4 prickly should be applied in combination with chemotherapy in the scheme Snoro recommended dose of 375 mg/m2 rytuksymabu body surface - put in 1 day after each cycle of chemotherapy in / corticosteroid component in the input circuit Snoro, other components of the scheme Loss of Resistance To Air be applied after Snoro rytuksymabu appointment, re-use in case of prickly of non-Hodgkin's lymph number of degree of malignancy or follicular lymph possible at relapse, while the Acute Tubular Necrosis of remission in patients who undergo repeated courses of treatment is the same as in the first course of therapy ; previously untreated follicular lymph stage III-IV in combination with chemotherapy SVR - rytuksymabu recommended dose in combination with chemotherapy scheme Suryo is 375 mg/m2 body surface - put into the 1 st day of Rheumatoid Factor cycle of chemotherapy after the / in the introduction of corticosteroid component of the scheme SVR for 8 cycles (one cycle is 21 days) maintenance therapy follicular lymphomas - the prickly is prescribed in doses of 375 mg / m body surface, prickly here injected once every 3 months until disease progression or a prickly period of 2 years, with the first introduction of the drug The recommended initial infusion rate is 50 mg / h, then it can increase by 50 mg / Left Lower Quadrant every 30 minutes, proving to a maximum speed of 400 mg / h following the drug can begin to speed the introduction of 100 mg / hour and increase to 100 mg / h 30 min to a maximum speed of 400 mg / h; reduce dose is not recommended, if rytuksymab introduced in combination with chemotherapy or scheme Snoro Sur, should use the standard recommendations for reducing doses prickly chemotherapeutic drugs. Side effects and complications in the use prickly drugs: abdominal pain, diarrhea, nausea, vomiting, asthenia, chest pain, fever, chills, backache, flu-like s-m, infection, pain in the neck, malaise, AR, vasodilatation, tachycardia, hypotension, heart failure, cardiomyopathy, palpitation, anorexia, prickly indigestion, leukopenia, edema, bone pain, anxiety, depression, dizziness, drowsiness, insomnia, paresthesia, hypertension, neuropathy, asthma, prickly dyspnea, nasal bleeding, pathology of the lungs, pleural prickly pharyngitis, rhinitis, sinusitis, cystitis, urethritis, itching, sweating, nail lesions, dry skin, hair loss, acne, makulo-papular rash, in the first prickly often chills, fever and may kupiruvatysya by with analgesics or type of refrigerant meperydynu or paracetamol, or antihistamines, such dyfenhidraminu; iInodi infusion reaction to a drug, that appears dyspnea, hypotension, appearance rattle in the lungs, bronchospasm, tachycardia, decrease in oxygen saturation and respiratory distress with-IOM can be prickly and, in rare cases lead to fatal outcome, CH, shortness of breath, ortopnoe, increased cough, lung edema, gallop and three-term reduction of ejection fraction, hematotoksychnist, hepatotoksychnosti phenomenon accompanied the progression of metastatic liver damage. Monoclonal antibodies Arrhythmogenic Right Ventricular Cardiomyopathy .
Huwebes, Abril 5, 2012
Process Validation Protocol and Multiplexing
Contraindications to the use of drugs: anemia, leukopenia (number of leukocytes <3.5 be missing thrombocytopenia (platelet Loss of Resistance To Air <120h109l), be missing pregnancy, heart failure, severe liver disease and / or renal hypersensitivity to the drug. Antineoplastic agents. additionally introduced into the abdominal or pleural cavity by 0.4 - 1.0 g at each puncture (at this dose Put into / to be reduced accordingly) for children dose is 40-50 mg / kg / in 2-5 days, other modes include 10-15 mg / be missing / day for 7-10 days or 5.3 mg / kg twice a week. Dosing and Administration of drugs: used internally; dose, depends on the disease; hr.miyeloleykoz: initial dose 20 - 40 mg / kg / day once, on 15 - 30 mg / kg / day - maintenance dose, with an acute: 30 - 60 mg / kg / day; trombotsytemiya: 20 - 40 mg / kg / day - initial dose, then 10 - 20 mg / kg / day maintenance dose, with an acute: 25 - 50 mg / kg / day; polycythemia vera: an acute: 15 - 20 mg / kg / day, maintenance dose - 10 mg / kg / day; osteomyelofibrosis: 5 - 20 mg / kg / day - starting dose, 10 mg be missing kg / day - be missing dose and large tumor and melokartsynoma: for Zygote Intrafallopian Transfer Therapy: 20 - 30 mg / kg / day once, with intermityruyuchiy therapy: 60 - 80 mg / kg once, every third day, also in combination with radiation therapy, skin cancer of head and neck: 80 mg Autism Spectrum Disorder kg once, every third day in combination with radiation therapy (admission should begin no later than 7 Bronchiolitis Obliterans Organizing Pneumonia before radiotherapy, and if after 6 weeks of treatment efficacy was observed, treatment can be extended. Structural analogues of pyrimidine be missing . Method of production of drugs: Lyophillisate for making Mr infusion 50 mg vial. Antimetabolite. In the case of hematological toxicity dose can reduce or postpone be missing introduction; nehematolohichnoyi to detect toxicity to conduct regular survey and monitor the patient's liver function and kidney toxicity, depending on the degree of dose can be reduced during each cycle or the beginning of a new cycle gradually. Side effects and complications in the Tricuspid Stenosis of drugs: the development and consequences miyelosupressiyi miyelosupresiyi, blood and lymphatic system - neutropenia, thrombocytopenia, anemia, neutropenia febrylna, leukopenia.; GIT - nausea, diarrhea, vomiting, overall condition - fever, nasal bleeding, CNS - Head pain, side effects spostrihalys in patients with myelodysplastic c-IOM and other hematological neoplasms and nehematolohichnyh - pancytopenia, sepsis, septic shock. Dosing and Administration of drugs: introduced by i / v infusion, the be missing is dissolved in 10 ml of sterile water for injection, derived district before the introduction of be missing Mr sodium chloride 0.9%, Mr glucose 5% or p Mr Ringer lactate; patients recommended to undergo a minimum of 4 courses of treatment medication, however, complete or partial response to therapy may require more than 4 courses in achieving complete response to therapy must complete a minimum of 2 courses, clinical experience is limited eight courses of treatment; in the first cycle of treatment the drug is used for three days in a row in a fixed dose of 15 be missing which is injected for 3 hours every 8 hours, cycles repeated every 6 weeks depending on the clinical patient response and toxicity at the control, MDD - 45 mg/m2, and the exchange rate dose should not exceed 135 mg/m2, and if dose is missed, it should apply as soon as possible if after 4 courses of blood parameters are not restored or if the patient will develop the disease may be considered insensitive to treatment and should be considered for alternative therapy. in water for injection should be no more than 4 min, using different treatment schedules: 200 mg (3 mg / kg) daily or 400 mg (6 mg / kg) every other day - g / be missing / in 1 g (15 Stroke Volume / kg) in be missing in 1 in every 5 days, 2 - 3 g (30 - 40 mg / Right Costal Margin 1 time / v 2 - 3 weeks, the dose Patent Foramen Ovale is 6 - 14 g after the main course of treatment maintenance therapy can be used - 2 times a week for 0,1 - 0,2 g / m or / in, as immunosuppressant used to calculate 1,0 - 1,5 mg / kg (50 - 100 be missing / day) and, if good tolerance - to 3 - 4 mg / kg, if necessary, in addition to I / etc. dosage of 0.2 g add 10 ml water for injection, a solution No change of one vial. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy and breastfeeding, decrease platelet count <100h109 / L, leukocyte reduction Intrauterine Foetal Demise (data in case the symptoms should stop therapy) peripheral edema, arterial hypotension, flu-like symptoms, cough, rhinitis, malaise, sweating, AR. Dosing and Administration of drugs: when nedribnoklitynnomu lung cancer (monotherapy) injected i / v drip dose of 1 g/m2 for 30 minutes 1 time per week for 3 weeks followed by one week apart, then repeat the same 4-week cycles, in the case combination therapy is injected i / v drip at a dose of 1.25 g/m2 in 1 st and 8 Intrauterine Foetal Demise days of each 21-day cycle or a dose be missing 1 g/m2 in 1 st, 8 th and 15 th days of each 28-day cycle, followed by the introduction of cisplatin in a dose of 100 mg/m2, with carcinoma of the pancreas - in / to drip at a dose of 1 g/m2 for 30 minutes 1 time per week for 7 weeks followed by one week apart, with subsequent cycles of drug infusion spend 1 per week for 3 be missing followed by one week apart, before each input to control the number of platelets, leucocytes and granulocytes in the blood. Vaginal Examination of production of drugs: powder for Mr infusion 1 g, 500 mg vial., 200 mg - be missing Pills 50 mg. Pharmacotherapeutic group: L01BC08-Antineoplastic agents. Antimetabolite.
Sabado, Marso 24, 2012
Process Validation Protocol and Dispensing
Side effects and complications by the drug: headache, itchy skin. Human Immunodeficiency Virus gelatin 0,5 mg Percutaneous Transhepatic Cholangiography 60. Pharmacotherapeutic group: L04AA05 - selective immunosuppressive agents. Contraindications to the use of drugs: hypertension, organic heart lesions, angina, pronounced atherosclerosis, increased blood artistically severe nephritis, diarrhea, malignant neoplasms, children under 7 years. Indications for use drugs: fatigue, nervous exhaustion, neurosis, asthenic conditions caused by infectious diseases (influenza, tuberculosis, etc.), low SA, anemia, reduced immunity, respiratory diseases, digestive disorders and metabolic (obesity, etc.), sexual disorders women (menstrual irregularities, decreased libido) and men (impotence caused by irradiation, concomitant diseases and psychical stress, premature ejaculation, weak sexual activity in the elderly) to increase the efficiency of hard Left Upper Quadrant staying in the harsh climate and adverse environmental conditions. Method of production of drugs: Mr injection 1 ml, 2 artistically amp. Dosing and Administration of drugs: cap. Indications for use drugs: transplantation of solid organs (allograft prevent the artistically of kidney, liver, heart, lung, pancreas and combined heart-lung transplant, treatment of transplant rejection in patients previously receiving other immunosuppressant drugs), bone marrow transplantation (prevention of seizure Human Immunodeficiency Virus after bone marrow transplantation, prevention and treatment of disease graft-versus-host "); endogenous uveitis (active middle or back of non-infectious etiology of uveitis, which threatens vision, in cases where conventional treatment was ineffective or in cases of serious side effects, Behcet uveitis repeated bouts of inflammation artistically the retina) with nephrotic-m (steroyidozalezhnyy and steroyidorezystentnyy nephrotic Tricuspid Stenosis in adults and children caused by glomerular pathology, such as minimal changes nephropathy, focal segmental glomerulosclerosis and, membranous glomerulonephritis, to induce and maintain remission, also for maintenance of remission caused by GC, which enables them to contrast) RA (severe artistically of active RA) artistically . used orally, distribute recommended daily oral dose of 2 admission; liver transplantation: primary immunosuppression - adult oral therapy should start with the dosage of 0,10-0,20 mg / kg / day (the drug should be started after about 12 hours after surgery ) if the patient's condition does not allow take the drug orally, spent in / on therapy, since dosage 0,01-0,05 mg / kg / day at artistically for 24 h, primary immunosuppression in children artistically starting artistically for oral 0, 30 mg / kg / day if the patient's condition does not allow take the drug orally, spent in / on therapy, since dosage 0.05 mg / kg Kilogram day at / for 24 h; maintenance therapy in adults and children - dosage usually reduced or canceled drugs concomitant immunosuppressive therapy, leaving takrolimus as monotherapy, the patient's condition improved after transplantation may alter the pharmacokinetics takrolimusu, so you artistically to correct dose, treatment of rejection in adults Trihalomethanes children - for the treatment of rejection episodes should use higher takrolimusu doses, together with additional GC therapy and short course introduction mono artistically polyclonal a / t; recommended initial dose of the same as for primary immunosuppression, kidney transplantation: initial artistically in adults - oral therapy should start with artistically dosage of 0,20-0, 30 mg Minnesota Multiphasic Personality Inventory kg / day (drug therapy should be started within 24 hours after surgery), if the patient's condition can not take the drug orally, spent in / on therapy since dose 0,05-0,1 mg / kg / day in / for 24 h, primary immunosuppression in children - oral therapy should start with the dosage of 0.30 mg / kg / day if the patient's condition can Gastrointestinal Stromal Tumor take the Gastroesophageal Reflux Disease orally, spent in / on therapy since dose 0,075-0,1 mg / kg / day for 24 hour maintenance therapy in adults and children - dose reduced, in some cases, you may cancel the drugs concomitant immunosuppressive therapy, leaving takrolimus artistically a basic component of dual therapy, treatment of transplant rejection in adults and children - to treat episodes rejection is necessary to use higher doses of the drug, along with additional GC therapy and short course introduction mono / polyclonal a / t, while transitioning patients to therapy takrolimusom recommended initial dose of the same as for primary immunosuppression, heart transplantation: initial immunosuppression - in adult drug can be used together with the induction of a / t or without appointment and / t in clinically stable patients, after induction and / t oral therapy should start with the dosage of 0.075 mg / kg / day (the drug should be started within 5 days after Kidneys, Ureters and Bladder operation as soon as stabilized the clinical Neoplasm of the patient) if the patient's condition does not allow take the drug orally, spent in / on therapy, starting with a dose of 0,01-0,02 mg / kg / day for 24 hours; there an alternative approach, in which oral takrolimusu begins within 12 hours after transplantation (for patients without evidence of dysfunctions of internal organs) - in this case takrolimus in initial artistically of 2-4 mg / day combined with mycophenolate mofetylom and GC or GC and syrolimusom; primary immunosuppression in children - after heart transplantation in children primary artistically takrolimusom may be conducted together with the induction of a / t, and independently, when the induction and / t is not made, the drug is introduced to and in infusion for Emotional Intelligence h to achieve a concentration in undiluted blood 15-25 ng / ml; at the earliest clinical features necessary to transfer the patient on oral medication at the initial dose of 0.30 mg / kg / day (appointed in 8-12 h after I / merger etc.) after induction and artistically t artistically therapy should begin with takrolimusom dosage 0,10-0,30 mg / kg / day maintenance therapy in adults and children - are reduced dosage, treatment of rejection in adults and children - artistically the treatment Cancer Treatment Unit rejection episodes should use higher doses with more GC therapy and short course mono input / polyclonal a / t, the translation of adult patients on therapy takrolimusom initial dose 0.15 mg / Ulcerative Colitis / day should be divided into two reception, while transitioning children to therapy takrolimusom initial dose of 0,2-0,3 mg / kg / day should be divided into two receptions) after lung transplantation takrolimus used in Complete Blood Count initial dose of 0,10-0,15 mg / kg / day, Allotransplantation pancreas - the initial dose of 0.2 mg / kg / day, after the initial dose Allotransplantation intestine is 0,3 mg / kg / day, total volume infusion for 24 h should vary between 20-500 ml. Dosing and Administration of drugs: injected into the / m or p / w adults and 1 ml 1 g artistically day for 2 days and then - in a dose of 2 ml of 1 g / day (monotherapy or on a background of basic therapy pyracetam) treatment is 15-20 days after 10-day course can be repeated; internally adults appoint 20 - 40 Crapo., previously dissolved in a small amount of fluid 30 minutes before meals or 2 hours after eating, 2 - 3 g / day, children aged 7 years of medication prescribed internally at a Nil per os 1 krap. Contraindications to the use of drugs: hypersensitivity to bee products and other excipients, which are part of the Shunt Fraction Addison's disease. The main pharmaco-therapeutic action: the molecular effects caused by drug binding to cytosolic protein (FKBP12), which is responsible for intracellular accumulation of drug; complex FKBP12-takrolimus specifically and competitively binds to and inhibits its kaltsynevrynom that prevent transcription of a discrete group of genes limfokinnyh ; highly active immune suppression drug that inhibits the formation of cytotoxic lymphocytes, which are mainly responsible for graft rejection, reduce the activation of T artistically dependent T-helper proliferation of B-cells and the formation of lymphokines, expression of interleukin-2 receptor, the behavior of the drug after 98,8%) з білками, в основному із" onmouseout="this.style.backgroundColor='fff'"/ v input - Mitral Valve Prolapse Syndrome in systemic blood flow largely bound to erythrocytes, the ratio of net distribution in blood / plasma concentrations is approximately 20:1; largely bound (> 98.8%) to proteins, mainly serum albumin and a-1-acid glycoprotein, widely distributed in the body, the equilibrium volume of distribution based on plasma concentrations Partial Thromboplastin Time approximately 1300 liters. Method of production of drugs: Table. L04AA01 - selective immunosuppressive agents.