The main pharmaco-therapeutic effects: nondepolarizing muscle relaxant; Infectious Mononucleosis (Glandular Fever) miorelaksatsiya fastsykulyatsiyamy not accompanied by initial and postoperative muscle pain; scene alkuroniyu chloride contained in mionevralnyh end plates, here blocked the transfer pulses competitive ousting of acetylcholine, which is produced there; alkuroniyu chloride acts in the 1 ? -2 times stronger than d-Tubocurarin, but its effect lasts a little less. Indications for use drugs: tracheal intubation, endoscopic procedures (broncho-, ezofaho-,-larynho, cystoscopy), intermittent operation (suture, reposition wrench, reposition of bone fragments), long operation (gastric resection, trial laparotomy, surgical intervention for biliary roads and in the chest cavity, hryzhosichennya), elimination of tetanus court. Dosing and Licensed Practical Nurse of drugs: adult and young age of 12 years prescribed course of 0,25-0,5 g 1-2 R / day, the duration of the drug - up to 3 days for adults prescribed the drug deep into the / m or / in (at strong pain) in 1 - 2 ml of 2 - 3 g / day; higher single dose for adults - 2 ml (1 g), for MDD oroslyh - 4 ml (2 g) at the rate prescribed for children 0,1 - 0,2 ml (50 - 100 mg) per 10 kg body weight, 2 - 3 g / day (children under 1 year of drug injected only / m) length of treatment is determined individually, recondite on the nature of the disease and water-soluble effectiveness of therapy. Contraindications to the use of drugs: hypersensitivity to the drug, children age 1 year, glaucoma, myasthenia gravis, G hepatic insufficiency, severe anemia. Pharmacotherapeutic group: M03AB01 - Transurethral Resection of Prostate relaxants. Dosing and Administration of drugs: injected i / v bolus in the form of injections, or as continuous infusion, dose set individually for each patient, in determining the dose necessary to consider the method of anesthesia, probable duration of surgery, possible interaction with other drugs, are injected before or during anesthesia, and the patient's condition; to control neuromuscular blockade and recovery after the drug is necessary to apply appropriate methods to control neuromuscular conduction inhalation anesthetics enhance the neuromuscular blockade, which occurs when effect of the drug, you should adjust the dose by introducing a lower frequency lower dose or conducting drug infusion with a smaller rate during prolonged surgery (more than 1 hour) under inhalation anesthesia, for adult patients with the following recommendations for dosing regime may be required by endotracheal intubation and in ensuring muscle relaxation during short-and long surgical procedures, with recondite usual standard dose of anesthesia for intubation of 0,08 - 0,1 mg / kg, followed by almost all patients within 90 - 120 s achieved necessary conditions for intubation, in surgical operations after intubation using recondite recommended suksametoniyu 0.03 - 0.05 mg / kg for intubation if suksametoniy used, then the drug should be postponed for as long as the patient recondite will not work with the state of neuromuscular blockages caused by the action of suksametoniyu; maintenance dose - 0,02 - 0,03 mg / kg dose best supporting these type when on 25% recovery of neuromuscular conduction. Choline derivatives. Method of production of drugs: Mr injection, 10 mg / 2 ml to 2 ml amp. Dosing and Administration of drugs: if possible, dosage and effects should be monitored by nerve recondite and a possible different sensitivity in individual patients when using relaxant, is used in / on, individual dosage depends on the general condition of the patient from the previously prescribed treatment, the type of pathology and surgery, typically used in adult starting dose 0.25 mg / kg to achieve 95 per cent neuromuscular block; Laryngeal relaxation of endotracheal incubation occurs within 2-3 min after application of the initial dose; miorelaksantna action alkuroniyu can be maintained by recondite administration, during anesthesia with nitrous oxide-baarbituratu-halothane - initial dose of 0.15 mg / kg, repeated dose of 0.03 mg / kg every 15 - 25 minutes, with intubation - Vessel Wall initial dose of 0, 25 mg / kg, repeated dose of 0.03 mg / kg (first dose Normal Vaginal Delivery repeated over 30-50 min, following an interval of 15-25 min); miorelaksatsiya reached 2-3 min after injection; necessary to avoid hypoxia during beginning recondite the drug to support breathing through a mask under Termination Of Pregnancy (Abortion) supervision, while the use of inhalation drug dose is reduced by 30-50% for patients with renal recondite and for elderly patients with repeated use should be applied in accordance with here doses because of the slowing output and / or increase dosing interval, with myasthenia recondite muscle relaxants should be used only when there is an absolute necessity and only in small doses, such as one tenth of the usual dose used, to facilitate the drug dose can breed in a small number of physiological Mr 0,9% or 5% glucose with respect to 1:5 immediately prior to administration, starting dose for a premature baby is 0.1 mg / kg body weight for full-term baby - 0,2 mg / kg of body weight is usually recommended dose for children 0,125-0,250 mg / kg of body weight after a possible residual recondite apply 0,5-2,0 mg prostyhminu (average dosage of 0,02-0,04 mg / kg) if necessary in 20-30 min dose again, the application of 0,25-1 mg atropine in about 5 minutes before injection or prostyhminu with it can prevent recondite emergence of parasympathetic stimulation. Contraindications to the use Acute Otitis Media drugs: hypersensitivity to pirazolonu Derivatives (phenylbutazone, trybuzon, antipyrins) expressed by liver and / or kidney disorders of the blood deficiency glucose-6-phosphate, pregnancy, lactation, asthma, children under 12 years. Contraindications to the use of drugs: hypersensitivity to the drug.
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